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Identity confirmed by LC-MS
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Third-party lab tested
8 Apr 202699.42% purityIdentity & purity testedLot 395387
Lab report published: 99.42% purity, lot 395387
MOTS-c
For research and laboratory use only. Not for human or animal consumption.
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Storage & handling: Store at 2–8 °C (≤ –20 °C long-term), away from light. Ships at ambient temperature.
How we test
Certificates are issued by independent labs. Identity and purity are measured by LC-MS; endotoxin, where listed, by a LAL screen. The latest report for this option: Identity & purity tested, lot 395387, tested 8 Apr 2026.
How to read your COA
Start with the lot number on the report. Identity confirms by mass spectrometry that the molecule is the one on the label. Purity is the share of the sample that is the target peptide, measured by LC-MS. Endotoxin, where tested, is screened by LAL and must sit below 0.5 EU/mL. The lab name and test date show who ran it and when.
Shipping
Regular tracked: $15 per order, 5 to 10 days. Express tracked: $25 per order, 3 to 5 days. Orders are dispatched within 24–48 business hours. Regular shipping is free on orders over $200 and express on orders over $400, after discounts.
Research & Education Tool
Peptide Dosage Calculator
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Buy MOTS-c peptide exclusively for research applications in qualified laboratories and academic institutions. Our platform provides secure ordering processes for institutional buyers and research coordinators. We offer discreet and reliable delivery to research facilities nationwide. The formulation is available in standardized configurations to support various research requirements. When you order MOTS-c peptide through our system, complete quality documentation is included. This product cannot be sold for human consumption or veterinary applications. No prescription is required for qualified research institutions to buy MOTS-c peptide online.
Product overview
Researchers investigate mitochondrial peptide behavior using MOTS-c in experimental models. Mitochondrial peptide research examines molecules produced by cellular energy-generating organelles. Laboratory teams explore cellular energy signaling studies in controlled research settings. Energy signaling studies investigate how cells communicate information about energy status. Scientists conduct controlled experimental peptide research under various laboratory conditions. Research groups examine how mitochondrial peptides function in cellular communication systems. These studies occur exclusively in research environments without clinical applications.
Research focus
MOTS-c is investigated in research environments for mitochondrial peptide analysis. Scientists have studied this compound within controlled laboratory models using standardized protocols. The formulation is explored for experimental mitochondrial peptide research in academic facilities. Researchers evaluate the peptide under controlled conditions without outcome claims.
Methodological notes
Store MOTS-c in cool, dry, light-protected conditions between 2-8°C. Light-protected conditions mean storage away from direct sunlight and intense artificial lighting. This product is intended for laboratory handling only by qualified research personnel. Qualified personnel have received appropriate training in peptide handling and storage procedures. Avoid moisture exposure as water content can affect peptide stability and quality. Avoid heat exposure above recommended temperature ranges to maintain structural integrity. Structural integrity refers to peptides maintaining their proper molecular configuration. Reconstituted solutions should follow established laboratory guidelines specific to peptide research protocols.
Quality & sourcing
Each MOTS-c batch undergoes comprehensive purity verification procedures through analytical testing. Analytical testing uses scientific instruments to measure peptide composition and quality. Our processes ensure batch-to-batch consistency across all research supply orders. Internal quality assurance standards follow research-grade supply positioning for peptide compounds. Research-grade supply means products meet specifications required for scientific laboratory use. Testing protocols verify peptide purity and structural characteristics using validated methods. Every unit meets our specifications before receiving distribution approval. Laboratory certificates accompany each order for institutional tracking and compliance documentation.
Chemical properties
- CAS: N/A
- Chemical Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
- Molecular Weight: 2174.64 g/mol
- Peptide Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Synonyms: Mitochondrial peptide, Mitochondria-derived peptide
- Shelf life: 24 months from the manufacturing date.
MOTS-c is a mitochondrial-derived peptide consisting of 16 amino acids in sequence. Mitochondrial-derived peptides are encoded by DNA within mitochondria rather than nuclear DNA. Mitochondria are cellular organelles responsible for generating energy in cells. Why mitochondrial peptides are studied in research relates to understanding cellular energy regulation. Energy regulation describes how cells manage their energy production and consumption. The general role of energy-related peptides in laboratory models includes serving as signaling molecules. Signaling molecules transmit information between different cellular components. Researchers investigate how this peptide interacts with cellular energy pathways. Cellular energy pathways are sequences of molecular reactions that produce usable energy.
Key features
MOTS-c provides a mitochondrial-derived research peptide developed for scientific applications. Mitochondrial-derived peptides are encoded by genetic material within cellular energy structures. Each batch undergoes high-purity testing to ensure compound consistency across orders. The formulation is designed for controlled laboratory environments conducting cellular research. Cellular research examines how molecules function within cell-based experimental systems. Secure packaging with discreet shipment protects the peptide during transit to research facilities.
Included
Express tracked
$25 per order · delivery in 3–5 days
- Tracked door to door, dispatched within 24–48 business hours
- Ambient shipping, safe for lyophilized peptides
Included
Regular tracked
$15 per order · delivery in 5–10 days
- Free on orders over $200
- Tracked door to door, dispatched within 24–48 business hours
What is MOTS-c and what is its biological origin?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded by the mitochondrial genome — specifically the 12S rRNA gene — making it part of the class of mitochondrial-derived peptides (MDPs). It is studied in research models as a mitochondria-to-nucleus and mitochondria-to-periphery signalling molecule that responds to metabolic stress. It is encoded within the small ribosomal RNA gene of the mitochondrial genome, an unusual location for a protein-coding sequence.
What signalling pathways has MOTS-c been studied for in preclinical research?
MOTS-c research has examined its effects on AMPK pathway activation in metabolic cell models, AICAR-related purine metabolite accumulation, mitochondrial biogenesis pathway signalling, and insulin sensitisation in skeletal muscle and hepatocyte research systems. Studies have also investigated its nuclear translocation in response to metabolic stress, where it reportedly interacts with promoter regions of stress-response genes to alter transcription.
What in vitro systems are used to study MOTS-c?
Standard in vitro models for MOTS-c research include L6 and C2C12 skeletal muscle cell lines for glucose uptake and AMPK activation studies, primary hepatocyte cultures for hepatic metabolic pathway analysis, and stressed cell models (H2O2, nutrient deprivation) for mitochondrial stress response characterisation. AICAR and metformin serve as reference AMPK-activating compounds in parallel assay systems.
How should MOTS-c be reconstituted and stored?
Lyophilised MOTS-c should be stored at -20°C. Reconstitution in sterile water or PBS is standard. Due to its small size (approximately 2200 Da) and moderate hydrophilicity, MOTS-c is typically soluble in aqueous buffers without organic co-solvents. Solutions should be aliquoted and stored at -80°C for extended use.
Is MOTS-c intended for human administration?
MOTS-c as supplied by Elivena is for research use in controlled laboratory settings only. It is not approved for human therapeutic, performance, or anti-ageing administration outside of formally regulated research contexts.
What is MOTS-c supplied for?
It is supplied exclusively for laboratory-based investigation of mitochondrial-associated metabolic signaling pathways under controlled in-vitro conditions.
Is this compound approved for therapeutic or clinical use?
No. MOTS-c is not approved for human or veterinary applications and is furnished strictly for research purposes.
How is product purity verified?
Each production lot undergoes independent third-party analytical testing confirming a minimum purity threshold of 99 percent. Certificate of Analysis documentation is available.
Lab report for lot 395387
View all lab reportsCertificate of analysis
99.42%
Purity by LC-MS
- Lot · 10 mg
- 395387
- Tested
- Apr 8, 2026
- Labeled
- 10 mg
- Measured
- 12.62 mg
LC-MS · independent lab
View certificate | Test | Method | Result | Status |
|---|---|---|---|
| Identity | LC-MS | Confirmed MOTS-c | PASS |
| Purity | LC-MS · spec >99% | 99.42% | PASS |
| Net content | LC-MS quantitation | 12.62 mg of 10 mg | PASS |
| Appearance | Visual | White lyophilized | REPORTED |
| Endotoxin | LAL | — | NOT TESTED |
No certificate is on file for the 20 mg option yet. On file for:
Batch tests: Purity
1 lab report available to signed-in researchers.
- CAS: N/A
- Chemical Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
- Molecular Weight: 2174.64 g/mol
- Peptide Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Synonyms: Mitochondrial peptide, Mitochondria-derived peptide
- Shelf life: 24 months from the manufacturing date.
MOTS-c is a mitochondrial-derived peptide consisting of 16 amino acids in sequence. Mitochondrial-derived peptides are encoded by DNA within mitochondria rather than nuclear DNA. Mitochondria are cellular organelles responsible for generating energy in cells. Why mitochondrial peptides are studied in research relates to understanding cellular energy regulation. Energy regulation describes how cells manage their energy production and consumption. The general role of energy-related peptides in laboratory models includes serving as signaling molecules. Signaling molecules transmit information between different cellular components. Researchers investigate how this peptide interacts with cellular energy pathways. Cellular energy pathways are sequences of molecular reactions that produce usable energy.
Read the lot first.
Identity confirmed
LC-MS confirms the molecule in the vial is MOTS-c.
Purity measured
The same LC-MS run measures the share that is the target peptide.
Lot-linked report
Each report names the lot it was run on.
Each lab report is tied to its lot.
Reports are issued by independent labs and name the lot they were run on.
How we test
Lab reportIdentity & purity tested, for the lot tested.
Lot numberPrinted on the report, so you can see which lot was tested.
Step 1
Synthesis and lyophilization
Synthesized and freeze-dried in US facilities, then given a lot number.
Step 2
Samples go to third-party labs
Finished vials from the lot are sent to independent labs.
Step 3
LC-MS: identity, purity, net content
One run confirms the molecule and measures its purity.
Step 4
LAL endotoxin screen
Bacterial endotoxin is checked against a 0.5 EU/mL limit.
Step 4
Certificate published
The summary goes on the product page; full PDFs are for signed-in researchers.
Store at 2 to 8 °C. Keep sealed and away from light until use.
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Shipping options
Dispatched in 24–48 business hours.
Regular tracked$15 per order · 5 to 10 days
Express tracked$25 per order · 3 to 5 days
Free shippingRegular over $200 · express over $400, after discounts
Testing that sets a higher standard.
Certificates come from independent labs, and each result sits next to its method.
Independent labs
Identity and purity by LC-MS
Researchers often ask
Is MOTS-c for human use?
No. MOTS-c is sold for laboratory research only. It is not for human or veterinary use, and it is not a drug, food or cosmetic.
How do I find the lab report?
Use View COAs on the product page, or search the COA library by compound name. The summary is public; the signed PDF reports are available to signed-in researchers.
Why is purity measured by LC-MS?
LC-MS separates the sample and identifies each component by its mass, so one run confirms identity and measures purity.
When will my order ship?
Orders are dispatched within 24–48 business hours. Regular tracked delivery takes 5 to 10 days and express tracked 3 to 5 days. Regular shipping is free on orders over $200 and express on orders over $400, after discounts.
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